Neuronal Activity in Tumor Tissue. Progress in Experimental Tumour Research, Volume 39. F Entschladen

ISBN:

Published: January 10th 2010

ebook

167 pages


Description

Neuronal Activity in Tumor Tissue. Progress in Experimental Tumour Research, Volume 39.  by  F Entschladen

Neuronal Activity in Tumor Tissue. Progress in Experimental Tumour Research, Volume 39. by F Entschladen
January 10th 2010 | ebook | PDF, EPUB, FB2, DjVu, talking book, mp3, RTF | 167 pages | ISBN: | 9.27 Mb

This book summarizes the current knowledge on how tumors interact with the nervous system and what impact this might have for the progression and treatment of cancer. It begins with an introduction to the organization and physiology of the nervous system, especially of the peripheral nervous system with its high degree of plasticity. Subsequent chapters discuss the interaction between peripheral nerves and tumor cells, the so-called neuro-neoplastic synapse, with regard to carcinogenesis, predictive tumor markers, tumor growth and tumor progression leading to metastasis.

In this part, the concept of neoneurogenesis is postulated as a process by which the tumor regulates its own innervation through the release of neurotrophic factors, in analogy to the process of neoangiogenesis discovered three decades ago. Once nerve endings have grown into the tumor, these can release neurotransmitters which promote tumor cell migration and metastasis development.

The final chapters reflect on the role of stem cells in neoneurogenesis and consider pharmacological approaches for the inhibition of neuro-neoplastic interactions as a basis for new anticancer therapies. Targeted primarily at investigators in experimental and clinical oncology, this book is also of special interest to neurobiologists as well as developmental and cell biologists.



Enter the sum





Related Archive Books



Related Books


Comments

Comments for "Neuronal Activity in Tumor Tissue. Progress in Experimental Tumour Research, Volume 39.":


cdkam.pl

©2014-2015 | DMCA | Contact us